Cancer Immunotherapy Principles and Practice

ISBN: 9781620700976
ISBN-10: 1620700972
Copyright: 2017
Edition: 1st
Editor: Butterfield, Lisa H., Kaufman, Howard L., Marincola, Francesco M.,
Doody's Expert Review    Score: 100
Reviewer: Ravi Salgia,  MD, PhD  (City of Hope)
At almost 900 pages, this is a comprehensive treatise on both FDA-approved and investigational immunotherapies for a variety of cancers. It not only covers the clinical aspects but also explains the basic science underlying these applications. Edited by established scientists and written by experts in their respective fields, this book, which is supported by the Society for Immunotherapy of Cancer, is an authoritative reference on this field at the interface of classical immunology and cancer biology.
The main purpose is to collate an authoritative compendium of important information illustrating the potential of the immune system in treating cancer. In doing so, the book underscores the clinical responses new immunotherapy agents have demonstrated, whether checkpoint inhibitors or adoptively transferred immune effector cells, and the corresponding survival benefit for patients with advanced cancer.
This book provides cutting-edge insights for every translational investigator and practicing clinician who yearns to learn and understand cancer immunology. It is also intended for a wider audience that includes cancer biologists, immunologists, and scientists interested in developing new immunotherapies for cancer. Those involved in healthcare management and regulatory affairs of these new types of therapies also may find this book a great resource.
The book is well conceived and well organized into five broad sections. Each section is overseen by a dedicated editor to provide a succinct overview of what is to follow. Section I (chapters 2-14) covers the basic principles of tumor immunology, section II (chapters 15-24) deals with cancer immunotherapy targets and classes, and section III (chapters 25-38) is devoted to immune function in cancer patients. Section IV (chapters 39-52) comprises the disease-specific treatments and outcomes. The final section (chapters 53-55) is the smallest and discusses the regulatory aspects of cancer immunotherapy. The introduction to each section and each chapter is well written and organized with adequate display items and references to the current literature. But the first chapter, which provides a captivating and enthralling historical perspective and recognizes those who pioneered and championed the field since the 19th century, is truly a delight to read.
Given the important and exciting advances in cancer immunotherapy, it is not surprising that there is no dearth of books on the subject. For example, Immunotherapy of Cancer: An Innovative Treatment Comes of Age, Yamaguchi (Springer, 2016), is just one of the more recent books on the topic, in addition to a number of books aimed at patients and non-oncologists. Despite the competition, however, this book is a unique masterpiece and a must-have comprehensive resource for anyone interested in this area and for every medical library.
Review Questionnaire
Range Question Score
1-10 Are the author's objectives met? 10
1-10 Rate the worthiness of those objectives. 10
1-5 Is this written at an appropriate level? 5
1-5 Is there significant duplication? (1=significant, 5=insignificant) 5
1-5 Are there significant omissions? (1=significant, 5=insignificant) 5
1-5 Rate the authority of the authors. 5
1-5 Are there sufficient illustrations? 5
1-5 Rate the pedagogic value of the illustrations. 5
1-5 Rate the print quality of the illustrations. 5
1-5 Are there sufficient references? 5
1-5 Rate the currency of the references. 5
1-5 Rate the pertinence of the references. 5
1-5 Rate the helpfulness of the index. N/A
1-5 If important in this specialty, rate the physical appearance of the book N/A
1-10 Is this a worthwhile contribution to the field? 10
1-10 If this is a 2nd or later edition, is this new edition needed? N/A