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eBook/Digital Version available from:

Web Site

Score: 94

Harrison's Principles of Internal Medicine - 2 Volume Set, 21st Edition

Doody's Core Title (2025 Edition)

Score(s):		2.53 (Health Sciences - Family Medicine)

ISBN: 978-1-264-26850-4, 3855 pages, Hard Cover
ISBN-10: 1-264-26850-5

2022

Edition:

21st

Editor:

Loscalzo, Joseph, MD, PhD; Fauci, Anthony S., MD; Kasper, Dennis L., MD; Hauser, Stephen L., MD; Longo, Dan L., MD; Jameson, J. Larry, MD, PhD

Specialties:

Family Medicine , General Internal Medicine , Primary Care

Publisher:

McGraw Hill

1325 Avenue of Americas, 7th Floor

New York, NY 10019

UNITED STATES

P: 800-338-3987 F: 800-953-8691

http://www.mhprofessional.com/medical

List Price:

$249.00

Brandon/Hill:

A version of this title appeared on the final Brandon/Hill list (2003/2004).

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Citation

Review

Questionnaire

At A Glance

The Voice of Clinical Reason

A Doody's Core Title for 2022!

Harrison?s Principles of Internal Medicine is the world's most trusted clinical medicine text - and a superb resource for learning the art and science of clinical reasoning. Recognized by healthcare professionals worldwide as the leading authority on applied pathophysiology and clinical medicine, Harrison?s Principles of Internal Medicine provides the informational foundation you need for the best patient care possible. This new edition is fully updated with timely new chapters and essential updates across the spectrum of internal medicine.

Written and edited by the world?s top experts in their respective fields, this landmark guide provides comprehensive, accurate, and essential coverage of the pathogenesis, diagnosis, and treatment of disease.

Harrison?s is world-renowned as the most authoritative source for:

Clear, concise schemas that facilitate the generation of differential diagnoses to reason efficiently through complex real world clinical cases
The physiologic and etiologic basis of signs and symptoms, which are covered through a wealth of unsurpassed expert guidance and linked to the disease-specific chapters that follow
Updated clinical trial results and recommended guidelines
Excellent and extensive visual support, including radiographs, clinical photos, schematics, and high-quality drawings
Coverage of both therapeutic approaches and specific treatment regimens
Practical clinical decision trees and algorithms
Organ/system-specific sections, with clinically relevant pathophysiology and practical clinical advice on the approach to the patient, strategies towards building a differential diagnosis, outstanding clinical algorithms and diagnostic schema, a wealth of clinical images and diagrams, current clinical guidelines, and general and specific approaches to therapy

Harrison?s remains the most trusted resource in a world influenced by endless sources of medical information. The most timely and comprehensive updates from the world?s top experts are featured in the 21st edition:

Current coverage of the diagnosis and treatment of diseases, from COVID to dementia to sepsis to multiple sclerosis to lung cancer
Updated content that reflects new approved therapeutics and new practice-changing guidelines and evidence summaries
More than 1000 clinical, pathological, and radiographic photographs, diagnostic and therapeutic decision trees, and clear schematics and diagrams describing pathophysiologic processes
Numerous atlases featuring curated collections of important visual aspects of diagnosis and management
Updated and time-saving curation and synthesis of established and new medical literature and studies
Clinically relevant coverage of disease mechanics and pathophysiology, and related therapeutic mechanisms

Learn more and order here.

Reviewer:	Alan Schwartzstein, BS, MD, FAAFP, ABFM Diplomate (SSM Health Dean Medical Group)

Description
This 21st edition arrives four years after the last edition, a time during which there have been significant advances in the understanding of health, along with the existence, prevention, and therapy of disease. The tome is divided into five sections, the first being an introduction to the profession of medicine along with current issues affecting the provision of health care. The second portion includes a valuable symptom and sign orientation to diagnosis, while the third and largest portion orients focus on the organ system and disease groups and the conditions in each. Each of these begins with an "approach" to (organ) diagnosis and treatment. The final portion of the book covers many issues not covered in the previous portion, such as poisoning and drug overdose, environmental illness, and a very impressive chapter on the approach to aging and care of geriatric patients.

Purpose
The purpose of this book is to serve as a comprehensive reference source on health and disease with a focus on practicing physicians and clinical presentations, summaries of psychophysiology, and treatment, as well as highlights of emerging frontiers of medicine and science. This is a worthy objective for primary care physicians as well as subspecialty clinicians who may provide diagnosis and treatment for these conditions, and the authors have met this goal admirably. As a family physician, this book meets my need for a reference that is easily accessible for my purposes, even if it does not have bedside/exam room value.

Audience
The audience for this book, according to the authors, is "learners throughout their careers." The book meets the needs of those in training, as it has for generations of physicians. For practicing physicians in adult medicine, the book is an excellent, authoritative, up-to-date source of medical knowledge. I like the balance between comprehensiveness and accessibility, which is useful for primary care clinicians without time for more complex, scientific tomes. The authors, many of whom wrote sections of previous editions, are recognized as experts in healthcare education and clinical application.

Features
I reviewed several chapters of the book, some of which had disease entities included in the differential diagnosis for patients in my practice. The writing is less academic and more accessible for the average clinical physician than prior editions. The first chapter on the practice of medicine nicely lays out the nature of our field as an art as well as a science. Another excellent pair of chapters toward the end of the book are on the aging process and geriatrics, which include important topics such as symptomatic care and addressing the ethical and moral issues that arise in these patients and families.

Assessment
This 21st edition will be a valuable resource on the bookshelf of any adult medicine physician. There are also many videos available online with the purchase of the book, making the price tag more understandable. For those who see predominantly older patients with complex presentations, particularly in rural and urban underserved areas, it is worth updating to this edition. If not, perhaps the 20th edition combined with CME such as UpToDate, the Medical and Prescriber's Letter, and live CME will suffice until the next edition.