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eBook/Digital Version available from:
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Score: 96 |
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| Gene Control, 3rd Edition |
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ISBN: 978-1-03-246546-3,
557 pages,
Soft Cover
ISBN-10: 1-03-246546-8 |
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| Copyright: |
2025 |
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| Edition: |
3rd |
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| Author: |
Latchman, David S.; Cheriyath, Venugopalan |
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Specialties:
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Genetics |
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| Publisher: |
CRC Press/Taylor & Francis Group |
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| List Price: |
$115.00 |
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| Google: |
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At A Glance
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The new edition of Gene Control, for the first time, provides extensive coverage on prokaryotic gene regulation, which makes it the only textbook offering a complete and detailed account of gene control for both prokaryotic and eukaryotic organisms. The core objective of this edition is to educate students about the fundamental principles and mechanisms governing gene expression, regulation, and function. To reinforce these ideas, each chapter now includes discussion questions to promote critical thinking. There are also multiple choice questions and animations for students, and a large question bank and figure slides for instructors. The textbook also emphasizes the vital role of scientific experiments and evidence in shaping our current understanding of gene control and provides comprehensive coverage of essential gene expression techniques and methodologies throughout the book. This extensively updated edition of the renowned textbook Gene Control will remain a valuable resource for students, instructors, researchers, and medical professionals exploring various aspects of gene control, ranging from the regulation of genes in infectious diseases to embryonic development across different organisms, from bacteria to humans.
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Reviewer:
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Mark Sanders,
PhD
(UC Davis College of Biological Sciences)
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Range
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Question
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Score
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| 1-10 |
Are the author's objectives met? |
10 |
| 1-10 |
Rate the worthiness of those objectives. |
10 |
| 1-5 |
Is this written at an appropriate level? |
5 |
| 1-5 |
Is there significant duplication? (1=significant, 5=insignificant) |
4 |
| 1-5 |
Are there significant omissions? (1=significant, 5=insignificant) |
5 |
| 1-5 |
Rate the authority of the authors. |
5 |
| 1-5 |
Are there sufficient illustrations? |
5 |
| 1-5 |
Rate the pedagogic value of the illustrations. |
4 |
| 1-5 |
Rate the print quality of the illustrations. |
4 |
| 1-5 |
Are there sufficient references? |
5 |
| 1-5 |
Rate the currency of the references. |
5 |
| 1-5 |
Rate the pertinence of the references. |
5 |
| 1-5 |
Rate the helpfulness of the index. |
4 |
| 1-5 |
If important in this specialty, rate the physical appearance of the book |
N/A |
| 1-10 |
Is this a worthwhile contribution to the field? |
10 |
| 1-10 |
If this is a 2nd or later edition, is this new edition needed? |
10 |
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Reviewer:
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Mark Sanders,
PhD
(UC Davis College of Biological Sciences)
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Description
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| The first edition of this textbook in 1990 focused on what was known about the regulation of gene expression in eukaryotic organisms. At the time, much of what was known about gene regulation in prokaryotes was thought to apply in some more complicated way to eukaryotes. The ensuing thirty-five years have proven that notion to be incorrect. Prokaryotes and eukaryotes have hugely different requirements and mechanisms of gene expression. The book provides a comprehensive overview of the normal and abnormal processes and mechanisms of gene expression in eukaryotes, with a small amount of coverage of bacterial gene expression and gene regulation discussed as background in the first two chapters of the book. |
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Purpose
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| The purpose of this book is to provide a comprehensive overview of the mechanisms and processes of the regulation of gene expression in eukaryotes primarily, but in bacteria as well for comparison and contrast. Designed as a textbook for advanced undergraduate students in a university course focused on gene regulation, the book provides detailed descriptions of gene regulation under normal and abnormal conditions in eukaryotes. It also gives basic descriptions of bacterial transcription, translation, and gene regulation in the opening two chapters. The discussion is accurate and up to date in nearly every area, making it a valuable contribution for student use. The book provides a thorough overview of eukaryotic gene regulation, and it is a worthy update to an out-of-date edition. |
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Audience
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| While advanced undergraduate students in molecular biology are the primary target audience for this book, graduate students studying aspects of eukaryotic gene regulation, and post-doctoral students studying gene regulation will find this book valuable as well. The book provides highly detailed descriptions of gene regulation in eukaryotes. Some of the in-depth discussions may be too much for an undergraduate molecular biology course. The detailed discussions, however, make the book valuable beyond undergraduate course usage, and it is the kind of book that serious students will keep for future reference. The senior author is widely experienced and is a recognized authority on all aspects of gene regulation in eukaryotes. |
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Features
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| Of the thirteen chapters in the book, excluding the introductory and concluding chapters, eleven are devoted to gene regulation in eukaryotes. Two chapters briefly cover bacteria gene regulation. The book can claim to cover prokaryotic and eukaryotic gene regulation, but the coverage is heavily biased in favor of eukaryotes. That is not necessarily a negative feature since eukaryotic gene regulation is highly complex and diversified under normal circumstances, and understanding how gene regulation goes awry is highly significant in understanding disease states and disease progression. The topical coverage of eukaryotic gene regulation in this book is broad. Beginning with chromatin structure and epigenetics, the majority of the book, nine chapters, discusses the regulation of transcription, translation, signaling pathways, the developmental control of gene expression, and gene expression in different cell types. The last two chapters of the book discuss gene regulation and misregulation in cancer, and gene regulation abnormalities in human disease. |
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Assessment
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| This is a valuable and worthy book. It provides a high level of detail on all the important aspects of gene regulation in eukaryotes. While the coverage of bacterial gene regulation is rather cursory, it provides helpful background to the main event of gene regulation in eukaryotes. This book comes with a strong positive recommendation. |
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