Extended Stability for Parenteral Drugs, 6th Edition

ISBN: 9781585285273
ISBN-10: 1585285277
Copyright: 2017
Edition: 6th
Editor: Bing, Caryn Dellamorte, Nowobilski-Vasilios, Anna ,
Doody's Expert Review    Score: 96
Reviewer: Lawrence Carey,  BS, PharmD  (Temple University School of Pharmacy)
While hospital pharmacies deal with 24-hour stability data, practitioners in home infusion practice must have stability data lasting a week or more. This is a compendium of extended stability data for 165 injectable drugs. The information for each drug is presented as a monograph highlighting pertinent concentrations, osmolality, appropriate diluents, and storage conditions. Additional standalone chapters describe how to apply this stability data and cover parenteral nutrition concepts. The previous edition was published in 2013.
The purpose is to provide "a continuing drug information project" to identify, review, and compile extended-use information in a concise format. Other landmark references are used as sources of information, such as Handbook on Injectable Drugs, 19th edition (American Society of Health-System Pharmacists, 2016), in collaboration with manufacturer data and previously published information. It is also meant to educate readers on vascular access devices, parenteral nutrition, and how to apply this expiration data to any sterile compounds that they may prepare. These are worthy objectives, as this book is necessary for those who practice in pharmacies that prepare extended-dated products.
The book is primarily for pharmacists and others (i.e., pharmacy technicians) who prepare sterile products. The authors have a wealth of experience and are outstanding, credible authorities in the area of sterile compounding.
The 165 individual monographs list the information necessary for successful preparation of sterile compounding such as diluents to use, manufacturers who make the drug available, and storage information. The book's strength is the number of anti-infectives covered, as that constitutes a large proportion of products that require extended-use data. The book's format has not changed from previous editions, but I find this predictability to be a plus. While not very "artsy," the book is useful and does not need additional graphics, although there are graphics that help explain vascular access devices.
This book is very useful for those who work in home infusion practices or any pharmacy venue where stability data needs to be extended. This is considered to be the foundation book for extended stability. Handbook on Injectable Drugs is much more targeted for hospital practice. This book serves as a nice supplement and addition to other books in any sterile products pharmacy's library. This book needs to be updated periodically, so this sixth edition is welcomed.
Review Questionnaire
Range Question Score
1-10 Are the author's objectives met? 8
1-10 Rate the worthiness of those objectives. 10
1-5 Is this written at an appropriate level? 5
1-5 Is there significant duplication? (1=significant, 5=insignificant) 4
1-5 Are there significant omissions? (1=significant, 5=insignificant) 5
1-5 Rate the authority of the authors. 5
1-5 Are there sufficient illustrations? 5
1-5 Rate the pedagogic value of the illustrations. N/A
1-5 Rate the print quality of the illustrations. N/A
1-5 Are there sufficient references? 5
1-5 Rate the currency of the references. 5
1-5 Rate the pertinence of the references. 5
1-5 Rate the helpfulness of the index. 5
1-5 If important in this specialty, rate the physical appearance of the book N/A
1-10 Is this a worthwhile contribution to the field? 10
1-10 If this is a 2nd or later edition, is this new edition needed? 10