Concepts in Clinical Pharmacokinetics, 6th Edition Doody's Expert Review Review Questionnaire ISBN: 9781585283873 ISBN-10: 1585283878 Copyright: 2014 Edition: 6th Authors: Spruill, William J., Wade, William E., DiPiro, Joseph T., Blouin, Robert A., Pruemer, Jane M., Doody's Expert Review    Score: 88 Doody's Star Rating™ and Doody's Expert Review provide by Doody Enterprises, Inc. Reviewer: Christina Rose,  PharmD  (Temple University School of Pharmacy) Description The first half of this thoroughly updated book discusses pharmacokinetic concepts and presents clinical examples and practice questions after each chapter, while the second half applies the pharmacokinetic concepts in chapters on the most commonly dosed drugs in clinical practice. Throughout, there are problems and discussion points, which may be used by instructors in classroom settings. The previous edition was published in 2010. Purpose The purpose is to introduce and explain important pharmacokinetic concepts and then use a stepwise approach to apply these concepts using clinical cases. Pharmacokinetics is a complicated topic that is important for pharmacists and pharmacy students to understand and apply to clinical scenarios. The authors do an exceptional job of explaining the concepts simply and clearly, and each chapter builds on the previous ones to allow the reader to gain a better understanding of the material. Audience Although the target audience appears to be pharmacy students, the book also would serve as a good refresher for residents and general pharmacists and pharmacy practitioners. The authors are all well-known pharmacy educators who are well qualified to write a book on this topic. Features Brief discussions and definitions of concepts related to pharmacokinetics and pharmacodynamics begin the book. The next lessons (chapters) go into more detail about each important pharmacokinetic parameter. The last four lessons review clinical dosing cases using the most commonly monitored drugs in clinical practice. This book presents many opportunities for readers to assess and apply what they have learned from each lesson, with multiple review questions and answers with explanations, as well as three sets of practice questions placed throughout the book to test understanding the of the previous few chapters. The frequent opportunities for assessment and feedback (with answers included) are strengths of this book. Each chapter contains numerous relevant clinical pearls to illustrate important points. The book also contains a glossary of abbreviations, definitions, and a multiple-page equation sheet which would be very helpful to students encountering this material for the first time. Assessment This is a useful reference for pharmacy students or practitioners looking to refresh their knowledge or skills. The material is presented in an easy to understand format, more so than other books on this topic. This update does expand on a few important clinical pharmacokinetic concepts: estimating renal function, extended-interval aminoglycoside dosing, and pharmacogenomics. These expanded sections are brief, yet needed additions. Review Questionnaire Range Question Score 1-10 Are the author's objectives met? 10 1-10 Rate the worthiness of those objectives. 10 1-5 Is this written at an appropriate level? 5 1-5 Is there significant duplication? (1=significant, 5=insignificant) 5 1-5 Are there significant omissions? (1=significant, 5=insignificant) 4 1-5 Rate the authority of the authors. 5 1-5 Are there sufficient illustrations? 5 1-5 Rate the pedagogic value of the illustrations. 5 1-5 Rate the print quality of the illustrations. 4 1-5 Are there sufficient references? 5 1-5 Rate the currency of the references. 3 1-5 Rate the pertinence of the references. 4 1-5 Rate the helpfulness of the index. 5 1-5 If important in this specialty, rate the physical appearance of the book N/A 1-10 Is this a worthwhile contribution to the field? 8 1-10 If this is a 2nd or later edition, is this new edition needed? 6 ©2024 Doody Enterprises, Inc.